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Hui Xie,1 Shengtao Tian,1 Li Cui,2 Jieyu Yan,2 Yanhua Bai,2 Xiaohui Li,2 Maoqiang Wang,2 Fangfang Zhang,3 Feng Duan21Department of Interventional Therapy, The Fifth Medical Center of PLA General Hospital, Beijing, 100039, People’s Republic of China; 2Department of Interventional Radiology, The First Medical Center of PLA General Hospital, Beijing, 100853, People’s Republic of China; 3Department of Outpatient, The Fifth Medical Center of PLA General Hospital, Beijing, 100039, People’s Republic of ChinaBackground: Transcatheter arterial chemoembolization (TACE) is one of the local therapies most commonly used to treat intermediate-stage or advanced-stage hepatocellular carcinoma (HCC). However, the clinical benefits of PA-TACE (postoperative adjuvant TACE) for improving prognosis (progress-free survival [PFS] or overall survival [OS]) of low-risk HCC patients with R0-stage HCC after hepatectomy were not very clear.Methods: From January 2005 to December 2012, 180 patients who underwent hepatectomy for HCC treatment were enrolled in this study, and the follow-up of these patients was ended in December 2017. Among these patients, 102 patients were performed PA-TACE 1 month later after R0 hepatectomy and 78 patients without adjuvant TACE after R0 hepatectomy. Survival analysis was calculated using the Kaplan–Meier statistical method. Differences between survival curves of different groups were tested using the univariate log-rank test. Multivariate Cox model was used to search for independent prognostic factors for progression or death and to acquire the adjusted HR.Results: PA-TACE significantly improved the survival of HCC patients received surgical resection. The PFS (progress-free survival) of PA-TACE group (median PFS 52.0 months; 95% CI: 14.0–90.0) was significantly longer than the control group (median PFS 11.1 months; 95% CI: [7.9–14.3]; log-rank P |
