Regioisomers Salviprolin A and B, Unprecedented Rosmarinic Acid Conjugated Dinorditerpenoids from Salvia przewalskii Maxim

Autor:	Xiangdong Su, Yichuang Wu, Meifang Wu, Jielang Lu, Shujie Jia, Xin He, Shuna Liu, Yuyang Zhou, Hui Xing, Yongbo Xue
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Salvia przewalskii Maxim Lamiaceae dinorditerpenoids rosmarinic acid 1 4-benzodioxane Organic chemistry QD241-441
Zdroj:	Molecules, Vol 26, Iss 22, p 6955 (2021)
Druh dokumentu:	article
ISSN:	1420-3049
DOI:	10.3390/molecules26226955
Popis:	Salvia przewalskii Maxim is a perennial plant from the genus Salvia (family Lamiaceae). The roots of S. przewalskii were long used as a traditional herb to treat blood circulation related illnesses in China. As part of our continuing interest in polycyclic natural products from medicinal plants, two unprecedented adducts comprised of a dinor-diterpenoid and a 9′-nor-rosmarinic acid derivative, linked by a 1,4-benzodioxane motif (1 and 2), were isolated from the roots of S. przewalskii. Their structures were established by extensive spectroscopic approaches including 1D, 2D NMR, and HRFABMS. Their cytotoxic activities against five human tumor cell lines were evaluated.
Databáze:	Directory of Open Access Journals
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