Nickel(II) N-Heterocyclic Carbene Complex for the Hydrogenation of 2-Acetylpyridine under Mild Conditions

Autor:	Mitu Sharma, Amanda M. Perkins, Alison K. Duckworth, Emily J. Rouse, Bruno Donnadieu, Bhupendra Adhikari, Sean L. Stokes, Joseph P. Emerson
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	N-heterocyclic carbene (NHC) nickel(II)-NHC complex hydrogenation 2-acetylpyridine Inorganic chemistry QD146-197
Zdroj:	Inorganics, Vol 11, Iss 3, p 120 (2023)
Druh dokumentu:	article
ISSN:	2304-6740
DOI:	10.3390/inorganics11030120
Popis:	Catalyst-mediated hydrogenation of ketones via hydride transfer can be directly used in the synthesis of alcohols which can exhibit great potential in the practical synthesis of pharmaceuticals. The application of Ni-NHC complexes in the hydrogenation of ketones is still limited. In a pursuit to study the effect of Ni-NHC-based complexes in the reactivity towards hydrogenation, we have studied the catalytic efficiency of a pendent-type nickel complex [Ni(NHC)2](PF6)2 constructed from a benzimidazole moiety. The hydrogenation of 2-acetylpyridine was studied with respect to catalyst loading, reaction temperature, reaction time, and solvent medium. The complex was broadly characterized by X-ray crystallography, ESI-MS, NMR, UV-Vis, and IR spectral studies.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/e60f83b14b7e46c4a5235e89db896a6a Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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