Intracellular hydrogelation preserves fluid and functional cell membrane interfaces for biological interactions

Autor: Jung-Chen Lin, Chen-Ying Chien, Chi-Long Lin, Bing-Yu Yao, Yuan-I Chen, Yu-Han Liu, Zih-Syun Fang, Jui-Yi Chen, Wei-ya Chen, No-No Lee, Hui-Wen Chen, Che-Ming J. Hu
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-019-09049-5
Popis: Cell membrane interface is mostly studied using synthetic bilayers and reconstituted cell membranes. Here the authors present a new cell fixation method in which the cytoskeleton is replaced by a synthetic hydrogel polymer network assembled inside the cell, thereby preserving the fluid membrane properties after cell death.
Databáze: Directory of Open Access Journals