Increased epicardial adipose tissue thickness is associated with microalbuminuria in hypertensive patients with left ventricular hypertrophy

Autor: Hayati Eren, Muhammed Bahadır Omar, Ülker Kaya, Lütfi Öcal, Mehmet İnanir, Aslı GÖzek Öcal, Ömer GenÇ, Selin GenÇ, Ahmet GÜner, Mucahit Yetİm
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Clinical and Experimental Hypertension, Vol 43, Iss 1, Pp 18-25 (2021)
Druh dokumentu: article
ISSN: 1064-1963
1525-6006
10641963
DOI: 10.1080/10641963.2020.1790588
Popis: Objective Epicardial adipose tissue (EAT) is a cardiometabolic risk factor, and its possible relationship with hypertension has been previously reported. Microalbuminuria (MA) is associated with target-organ damage, especially in patients with hypertension with left ventricular hypertrophy (LVH) and suggest endothelial dysfunction. This study aimed to investigate the relationship between echocardiographic EAT thickness and presence of MA in patients with hypertension. Methods A total of 297 newly diagnosed hypertension patients who applied to the outpatient clinic were enrolled consecutively in this study. Patients were divided into two groups regarding the presence of LVH in echocardiography. An age and gender matched control group was set including 156 healthy patients without HT. All subjects underwent transthoracic echocardiography for the measurement of EAT thickness. Spot urine samples were collected for the assessment of MA. Results In hypertensive patients with LVH, the EAT thicknesses (6.6 ± 1.8 vs 5.3 ± 1.5 vs 5.1 ± 1.3, p
Databáze: Directory of Open Access Journals
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