Autor: |
Xi Lin, Jiaying Zhang, Xiangwei Kong, Yanbin Li, Xueqin Xu, Lianjun Du, Jeff L. Zhang |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
Physiological Reports, Vol 12, Iss 15, Pp n/a-n/a (2024) |
Druh dokumentu: |
article |
ISSN: |
2051-817X |
DOI: |
10.14814/phy2.16171 |
Popis: |
Abstract Total amount of creatine (Cr) and phosphocreatine, or total creatine (tCr), may have a significant impact on the performance of skeletal muscles. In sports such as bodybuilding, it is popular to take Cr supplements to maintain tCr level. However, no study has explored the quantitative relationship between exercise intensity and the induced change in muscle's tCr. In this well‐controlled study, straight‐leg plantar flexion with specific load and duration was performed by 10 healthy subjects inside an MRI scanner, immediately followed by 1H MR spectroscopy (MRS) for measuring tCr concentration in gastrocnemius. For repeatability assessment, the experiment was repeated for each subject on two different days. Across all the subjects, baseline tCr was 46.6 ± 2.4 mM, ranging from 40.6 to 50.1 mM; with exercise, tCr significantly decreased by 10.9% ± 1.0% with 6‐lb load and 21.0% ± 1.3% with 12‐lb load (p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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