Levothyroxine absorption test – Results and follow up of patients from a single center

Autor: Karthik Subramaniam, Tom Babu, K C Sreevalsan, Shemy Mathew
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Indian Journal of Endocrinology and Metabolism, Vol 27, Iss 1, Pp 32-36 (2023)
Druh dokumentu: article
ISSN: 2230-8210
DOI: 10.4103/ijem.ijem_188_21
Popis: Introduction: Treating primary hypothyroidism with appropriate weight-based dosing is usually straightforward. When supraphysiologic doses of thyroxine are required, it is important to know the reason behind the increased requirement. When compliance with medication is assured and when there are no drug interactions resulting in increased thyroxine requirements, a levothyroxine absorption test (LT4AT) could be performed to diagnose the coexistence of malabsorption. Materials and Methods: This was a single-center, retrospective chart review. Patients who had undergone LT4AT between 2018 and 2020 with a complete evaluation and follow-up records were reviewed. LT4AT and further evaluation (if necessary) were standardized, and details until the last review were obtained. Results: In all, 11 patients had complete records and follow-up details. The median age (range) of the cohort was 24 years (19 to 46), and the duration of hypothyroidism was 8 years (4 to 24). Seven had low absorption (
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