| Autor: |
Jean Paul ten Klooster, Marianne Bol-Schoenmakers, Kitty van Summeren, Arno L. W. van Vliet, Cornelis A. M. de Haan, Frank J. M. van Kuppeveld, Saertje Verkoeijen, Raymond Pieters |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2399-3642 |
| DOI: |
10.1038/s42003-021-02176-0 |
| Popis: |
ten Klooster et al. use ileum-derived organoids and report that bacterial and viral stimuli can drive IL22 production by T cells via distinct signaling pathways, and that IL22 can stimulate expression of anti-microbial and antiviral factors. This study sheds light on how enterocytes, fibroblasts and myeloid cells work synergistically to induce IL22 response against both bacteria and viruses. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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