| Autor: |
Tripti Pandey, Gaurav Chhetri, Ramesh Chinta, Bijay Kumar, Dev Bukhsh Singh, Timir Tripathi, Arvind Kumar Singh |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
FEBS Open Bio, Vol 5, Iss 1, Pp 1-7 (2015) |
| Druh dokumentu: |
article |
| ISSN: |
2211-5463 |
| DOI: |
10.1016/j.fob.2014.11.006 |
| Popis: |
We report a novel class of glutathioneS‐transferase (GST) from the model cyanobacteriumSynechocystis PCC 6803 (sll1545) which catalyzes the detoxification of the water pollutant dichloroacetate and also shows strong glutathione‐dependent peroxidase activity representing the classical activities of zeta and theta/alpha class respectively. Interestingly, sll1545 has very low sequence and structural similarity with these classes. This is the first report of dichloroacetate degradation activity by any bacterial GST. Based on these results we classify sll1545 to a novel GST class, rho. The present data also indicate potential biotechnological and industrial applications of cyanobacterial GST in dichloroacetate‐polluted areas. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
Plný text