Autor: |
Nikolaj Frost, Martin Brünger, Christoph Ruwwe-Glösenkamp, Matthias Raspe, Antje Tessmer, Bettina Temmesfeld-Wollbrück, Dirk Schürmann, Norbert Suttorp, Martin Witzenrath |
Jazyk: |
angličtina |
Rok vydání: |
2019 |
Předmět: |
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Zdroj: |
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-10 (2019) |
Druh dokumentu: |
article |
ISSN: |
1471-2466 |
DOI: |
10.1186/s12890-019-1002-8 |
Popis: |
Abstract Introduction Recurrent pleural effusion is a common cause of dyspnoea, cough and chest pain during the course of malignant diseases. Chemical pleurodesis had been the only definitive treatment option until two decades ago. Indwelling pleural catheters (IPC) emerged as an alternative, not only assuring immediate symptom relief but also potentially leading to pleurodesis in the absence of sclerosing agents. Methods In this single-centre retrospective observational study patient characteristics, procedural variables and outcome in a large population of patients with IPC in malignancy were evaluated and prognostic factors for pleurodesis were identified. Results From 2006 to 2016, 395 patients received 448 IPC, of whom 121 (30.6%) had ovarian, 91 (23.0%) lung and 45 (11.4%) breast cancer. The median length of IPC remaining in place was 1.2 months (IQR, 0.5–2.6), the median survival time after insertion 2.0 months (IQR, 0.6–6.4). An adequate symptom relief was achieved in 94.9% of all patients, with no need for subsequent interventions until last visit or death. In patients surviving ≥30 days after IPC insertion, pleurodesis was observed in 44.5% and was more common in patients |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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