Challenges in diagnosing concurrent acute leukemia in an immunosuppressed patient with systemic lupus erythematosus: A case report

Autor: Shaily Agrawal, Amit K. Jangir, M Yogesh, Rohankumar Gandhi
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Family Medicine and Primary Care, Vol 13, Iss 11, Pp 5402-5406 (2024)
Druh dokumentu: article
ISSN: 2249-4863
2278-7135
DOI: 10.4103/jfmpc.jfmpc_874_24
Popis: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by damage to organs and cells, initially mediated by tissue-binding autoantibodies and immune complexes. Lymphomas have been frequently reported, but the association of SLE with acute leukemia is rare and likely coincidental. We report a case of a 40-year-old female admitted for an etiological diagnosis of fever and dyspnea with peripheral edema. She had a history of SLE diagnosed 2 years prior and had been on immunosuppressive therapy since then. Hematological investigations showed leukocytosis, anemia, and thrombocytopenia. Further diagnostic testing could not be done as she passed away 3 days after acute leukemia was diagnosed. This case highlights the challenges of diagnosing hematological malignancies in immunosuppressed SLE patients where symptoms may be obscured.
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje