Does regeneration recapitulate phylogeny? Planaria as a model of body-axis specification in ancestral eumetazoa

Autor:	Chris Fields, Michael Levin
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	bioelectricity bmp pathway eumetazoa nervous system symmetry breaking whole-body regeneration wnt pathway Biology (General) QH301-705.5
Zdroj:	Communicative & Integrative Biology, Vol 13, Iss 1, Pp 27-38 (2020)
Druh dokumentu:	article
ISSN:	1942-0889 19420889
DOI:	10.1080/19420889.2020.1729601
Popis:	Metazoan body plans combine well-defined primary, secondary, and in many bilaterians, tertiary body axes with structural asymmetries at multiple scales. Despite decades of study, how axis-defining symmetries and system-defining asymmetries co-emerge during both evolution and development remain open questions. Regeneration studies in asexual planaria have demonstrated an array of viable forms with symmetrized and, in some cases, duplicated body axes. We suggest that such forms may point toward an ancestral eumetazoan form with characteristics of both cnidarians and placazoa.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/60a510816d234da19956e0a113f5393c Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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