| Autor: |
Chengbo Liu, Jiuling Liao, Longchao Chen, Jianhua Chen, Rubo Ding, Xiaojing Gong, Caimei Cui, Zhiqiang Pang, Wei Zheng, Liang Song |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Photoacoustics, Vol 14, Iss , Pp 12-18 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2213-5979 |
| DOI: |
10.1016/j.pacs.2019.02.001 |
| Popis: |
A dual modality microscopy with the highest imaging resolution reported so far based on reflection-mode photoacoustic and confocal fluorescence is presented in this study. The unique design of the imaging head of the microscope makes it highly convenient for scalable high-resolution imaging by simply switching the optical objectives. The submicron resolution performance of the system is demonstrated via in vivo imaging of zebrafish, normal mouse ear, and a xenograft tumor model inoculated in the mouse ear. The imaging results confirm that the presented dual-modality microscopy imaging system could play a vital role in observing model organism, studying tumor angiogenesis and assessment of antineoplastic drugs. MSC: 00-01, 99-00, Keywords: Photoacoustic microscopy, Confocal microscopy, Multimodal imaging |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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