Management of pemphigoid vegetans with mycophenolate mofetil: A case report
Autor: | Audrey Mathieu, Myrna Chababi-Atallah, Hugues Allard-Chamard, Carolina Lucena Fernandes |
---|---|
Jazyk: | angličtina |
Rok vydání: | 2024 |
Předmět: | |
Zdroj: | SAGE Open Medical Case Reports, Vol 12 (2024) |
Druh dokumentu: | article |
ISSN: | 2050-313X 2050313X |
DOI: | 10.1177/2050313X241231535 |
Popis: | Pemphigoid vegetans is a rare variant of bullous pemphigoid. Only 13 cases have been documented in the medical literature. The lesions clinically resemble pemphigus vegetans, but the histology is consistent with bullous pemphigoid. We present the case of a 63-year-old woman with painful vesicular and vegetative lesions progressing for 4 months. Histopathology showed a dermal-epidermal cleavage, epidermal acanthosis and an eosinophilic infiltrate. Direct immunofluorescence showed linear deposition of IgG and IgA at the junctional level. The diagnosis of pemphigoid vegetans was retained and successfully treated with oral corticosteroid, dapsone and mycophenolate mofetil. |
Databáze: | Directory of Open Access Journals |
Externí odkaz: |