Management of pemphigoid vegetans with mycophenolate mofetil: A case report

Autor: Audrey Mathieu, Myrna Chababi-Atallah, Hugues Allard-Chamard, Carolina Lucena Fernandes
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: SAGE Open Medical Case Reports, Vol 12 (2024)
Druh dokumentu: article
ISSN: 2050-313X
2050313X
DOI: 10.1177/2050313X241231535
Popis: Pemphigoid vegetans is a rare variant of bullous pemphigoid. Only 13 cases have been documented in the medical literature. The lesions clinically resemble pemphigus vegetans, but the histology is consistent with bullous pemphigoid. We present the case of a 63-year-old woman with painful vesicular and vegetative lesions progressing for 4 months. Histopathology showed a dermal-epidermal cleavage, epidermal acanthosis and an eosinophilic infiltrate. Direct immunofluorescence showed linear deposition of IgG and IgA at the junctional level. The diagnosis of pemphigoid vegetans was retained and successfully treated with oral corticosteroid, dapsone and mycophenolate mofetil.
Databáze: Directory of Open Access Journals