Autor: |
Jie Liu, Grace John-Stewart, Barbra A Richardson, Indi Trehan, Ruchi Tiwari, Kirkby D Tickell, Mareme M Diakhate, Benson O Singa, Christine J McGrath, Patricia B Pavlinac, Doreen Rwigi, Judd L Walson, James A Platts-Mills, Eric R Houpt, Arianna Rubin Means, Churchil Nyabinda, Emily Yoshioka, Joyce Otieno, Adeel Shah, Lucia Keter, Maureen Okello, James M Njunge, Julius Nyaoke, Eric Ochola |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
BMJ Open, Vol 14, Iss 8 (2024) |
Druh dokumentu: |
article |
ISSN: |
2044-6055 |
DOI: |
10.1136/bmjopen-2023-079448 |
Popis: |
Introduction Children with moderate or severe wasting are at particularly high risk of recurrent or persistent diarrhoea, nutritional deterioration and death following a diarrhoeal episode. Lactoferrin and lysozyme are nutritional supplements that may reduce the risk of recurrent diarrhoeal episodes and accelerate nutritional recovery by treating or preventing underlying enteric infections and/or improving enteric function.Methods and analysis In this factorial, blinded, placebo-controlled randomised trial, we aim to determine the efficacy of lactoferrin and lysozyme supplementation in decreasing diarrhoea incidence and improving nutritional recovery in Kenyan children convalescing from comorbid diarrhoea and wasting. Six hundred children aged 6–24 months with mid-upper arm circumference |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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