Biochemical risk factors associated with refractory epilepsy: alpha synuclein and adenosine deaminase

Autor: Şener Nurdan, Keti Didem Barlak, Güleç Ayten, Canpolat Mehmet, Per Hüseyin, Gümüş Hakan, Muhtaroğlu Sabahattin
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Romanian Journal of Laboratory Medicine, Vol 32, Iss 3, Pp 255-261 (2024)
Druh dokumentu: article
ISSN: 2284-5623
DOI: 10.2478/rrlm-2024-0021
Popis: Epilepsy is a common chronic neurological disorder affecting all age groups. A significant portion of children with epilepsy develop drug-resistant seizures. These children are at risk of cognitive and behavioral comorbidities and death. Some clinical features provide important information about the prognosis of epilepsy. However, currently, there is no objective biochemical indicator associated with refractory epilepsy. This study aimed to determine whether serum alpha-synuclein (αS), pglycoprotein (P-gp), and adenosine deaminase activity (ADA) were biochemical risk factors for refractory epilepsy.
Databáze: Directory of Open Access Journals