Covalent Polymer-Drug Conjugates

Autor: A. Cifuentes, J. Roman, A. Gallardo, C. Elvira
Jazyk: angličtina
Rok vydání: 2005
Předmět:
Zdroj: Molecules, Vol 10, Iss 1, Pp 114-125 (2005)
Druh dokumentu: article
ISSN: 10010114
1420-3049
DOI: 10.3390/10010114
Popis: In this work, polymer-drugs conjugates used as drug delivery systems (DDS) are revised attending to their chemical conjugation. Namely, the classification of this type of DDS is based on the conjugation sites of the reactive groups (i.e., via end groups or pendant polymer groups). Advantages and limitations of these types of DDS are discussed through representative examples of polymer-drugs and polymer-proteins conjugates recently developed.
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