Conversion of α-Diazoketones into 1-Bromo-2-alkyl- or 2-arylpent-4-en-2-ols using Tin-Mediated Allylation/Propargylation

Autor: Swapan Kumar Biswas, Sipak Joyasawal
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: SynOpen, Vol 07, Iss 02, Pp 161-164 (2023)
Druh dokumentu: article
ISSN: 2509-9396
DOI: 10.1055/a-2068-5625
Popis: High-yielding and mild conditions are used to prepare of 1-bromo-2-alkyl- or 2-arylpent-4-en-2-ols/1-bromo-2-alkyl- or 2-arylpent-4-yn-2-ols from α-diazoketones. The reaction involves allylation/propargylation with successive bromide insertion using in situ generated allyltin bromide/or propargyltin bromide from activated tin metal and allyl/or propargyl bromide.
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