Factors affecting corneal deformation amplitude measured by Corvis ST in eyes with open-angle glaucoma
| Autor: | Zia S Pradhan, Shruthi Sreenivasaiah, Sujit Deshmukh, Lavi Mangala, Sujani Shroff, Sathi Devi, Carroll AB Webers, Harsha L Rao |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Indian Journal of Ophthalmology, Vol 72, Iss 4, Pp 533-537 (2024) |
| Druh dokumentu: | article |
| ISSN: | 0301-4738 1998-3689 |
| DOI: | 10.4103/IJO.IJO_822_23 |
| Popis: | Purpose: To evaluate the factors affecting corneal deformation amplitude (DA) measured using Corvis ST in eyes with open-angle glaucoma. Methods: This prospective, longitudinal study included 48 eyes with open-angle glaucoma who required additional intraocular pressure (IOP)-lowering drops. All eyes underwent a complete eye examination at baseline, including a Corvis ST, which was repeated 4–8 weeks after the change in therapy. Factors affecting the corneal biomechanics, namely the DA, were determined using mixed effect models. Results: The mean age of the cohort was 65.0 ± 7.9 years. The mean IOP reduced from 23.4 ± 5.4 mmHg to 17.9 ± 5 mmHg after the change in glaucoma treatment (P < 0.001). The DA increased from 0.89 ± 0.16 mm to 1.00 ± 0.13 mm after IOP reduction (P < 0.001). On mixed effect model analysis, IOP (−0.02 ± 0.001, P < 0.001) and corneal pachymetry (−0.0003 ± 0.0001, P = 0.02) affected the change in the DA. Conclusion: IOP and corneal pachymetry affect the DA and must be accounted for when using Corvis ST to evaluate corneal biomechanics in glaucoma. |
| Databáze: | Directory of Open Access Journals |
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