Concomitant use of dupilumab with glucocorticoid in bullous pemphigoid reduces disease severity: A preliminary study

Autor: Lingyu Hu, Ruiting Huang, Fuqiong Jiang, Shuqiong You, Qian Wu
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Immunity, Inflammation and Disease, Vol 11, Iss 7, Pp n/a-n/a (2023)
Druh dokumentu: article
ISSN: 2050-4527
DOI: 10.1002/iid3.924
Popis: Abstract Objective To retrospectively analyze the efficacy and safety of dupilumab in the treatment of bullous pemphigoid. Methods From October 2020 to October 2022, the medical records of patients with bullous pemphigoid who were treated with dupilumab in our department were collected retrospectively to analyze the therapeutic effect and changes in laboratory indexes. Results The records of a total of 11 patients with bullous pemphigoid who were treated with dupilumab was reviewed. Within 2 weeks of the treatment, 10 (90.9%) of the 11 patients had complete or substantial control of the disease. The BPDAI scores of the patients decreased from baseline 113 (62, 181) to 37 (6, 130) at 2 weeks (p = .001) and 4 (0, 37) at 12 weeks after treatment (p
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje