Creation of stable water-free antibody based protein liquids

Autor: Joseph M. Slocik, Patrick B. Dennis, Zhifeng Kuang, Anthony Pelton, Rajesh R. Naik
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Communications Materials, Vol 2, Iss 1, Pp 1-11 (2021)
Druh dokumentu: article
ISSN: 2662-4443
DOI: 10.1038/s43246-021-00222-2
Popis: Antibodies are widely used in biotechnology and bioengineering, but are sensitive to their environment. Here, primary antibodies are converted into thermally-stable protein liquids, achieving >60% antigen binding after cyclic heating at 125 °C and remain active when incorporated into plastics.
Databáze: Directory of Open Access Journals