Membranes are functionalized by a proteolipid code

Autor: Troy A. Kervin, Michael Overduin
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMC Biology, Vol 22, Iss 1, Pp 1-7 (2024)
Druh dokumentu: article
ISSN: 1741-7007
DOI: 10.1186/s12915-024-01849-6
Popis: Abstract Membranes are protein and lipid structures that surround cells and other biological compartments. We present a conceptual model wherein all membranes are organized into structural and functional zones. The assembly of zones such as receptor clusters, protein-coated pits, lamellipodia, cell junctions, and membrane fusion sites is explained to occur through a protein-lipid code. This challenges the theory that lipids sort proteins after forming stable membrane subregions independently of proteins.
Databáze: Directory of Open Access Journals
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