Proportion and number of incident cancer deaths in coronary artery disease

Autor:	Jin Liu, Shiqun Chen, Yang Zhou, Haozhang Huang, Qiang Li, Yan Liang, Shaohong Dong, Xiaoyu Huang, Liling Chen, Xueyan Zheng, Ruilin Meng, Congzhuo Jia, Jiyan Chen, Ning Tan, Yong Liu
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	cancer‐specific mortality cardio‐oncology coronary artery disease proportion spectrum Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Cancer Medicine, Vol 12, Iss 19, Pp 20140-20149 (2023)
Druh dokumentu:	article
ISSN:	2045-7634
DOI:	10.1002/cam4.6595
Popis:	Abstract Background Globally, coronary artery disease (CAD) and cancer are the leading causes of death. Studies focusing on the proportion and spectrum of cancer mortality among CAD patients are lacking. We aim to characterize the proportion and spectrum of cancer‐specific mortality among patients with CAD. Methods We analyzed 93,797 hospitalized survivors with angiographically documented CAD between 2007 and 2020 (mean age: 62.8 ± 11.1 years, 24.7% female) from Cardiorenal ImprovemeNt II (CIN‐II) cohort. Results During the median follow‐up of 4.8 years (IQR: 2.6–7.5), 13,162 (14.0%) patients died after discharge. A total of 1223/7703 (15.8% of cause‐specific death) CAD patients died of cancer. The three most common types of cancer‐specific death were lung (36.1%), liver (13.3%), and colorectum cancer (12.8%). Furthermore, male (adjusted HR 2.38, 95% CI: 1.99–2.85) and older (≥60 vs.
Databáze:	Directory of Open Access Journals
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