Identification of novel risk factors for postoperative severe hypocalcemia in patients with primary hyperparathyroidism undergoing parathyroidectomy: a case control study

Autor:	Jiahao Xu, Na Kong, Nan Bai, Ziqin Zhang, Aimin Cui, Shen Tan, Qiqi Xu
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Primary hyperparathyroidism Parathyroidectomy Postoperative severe hypocalcemia Hungry bone syndrome Serum phosphorus Osteocalcin Diseases of the endocrine glands. Clinical endocrinology RC648-665
Zdroj:	BMC Endocrine Disorders, Vol 24, Iss 1, Pp 1-9 (2024)
Druh dokumentu:	article
ISSN:	1472-6823
DOI:	10.1186/s12902-024-01620-6
Popis:	Abstract Background Patients with primary hyperparathyroidism (PHPT) are at risk for severe hypocalcemia (SH) following parathyroidectomy (PTX), but limited data exist on the predictors of SH. We aimed to identify risk factors for early postoperative SH after PTX in patients with PHPT and to evaluate the predictive value of clinical parameters. Methods A retrospective review of patients with PHPT who underwent PTX between January 2010 and December 2022 was performed. A total of 46 patients were included in the study, with 15 (32.6%) experiencing postoperative SH, 19 (41.3%) having calculi in the ureter or kidney, and 37 (80.4%) having osteoporosis. Patients were divided into SH and non-SH groups based on postoperative serum calcium levels. Preoperative biochemical indicators, bone turnover markers, and renal function parameters were analyzed and correlated with postoperative SH. Results Statistically significant (P
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/602ec7c4f74b4ba4a07b487d44b8aea4 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.