| Autor: |
Boutou Masky, Hamadjida Adjia, David Miaffo, Bibi Farouck Aboubakar Oumarou, Harquin Simplice Foyet, Kakesse Maguirgue, Ernest Rodrigue Talla, Angele Kopodjing Bello, Christian Bonabé, Fidèle Ntchapda |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Metabolism Open, Vol 22, Iss , Pp 100288- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2589-9368 |
| DOI: |
10.1016/j.metop.2024.100288 |
| Popis: |
Backgroud: Erigeron floribundus is a herbaceous plant used in traditional Cameroonian medicine to treat diabetes mellitus. The aim of this study was to evaluate the antidiabetic properties of the aqueous extract of E. floribundus leaves (AEEF) in diabetic rats. Methods: Diabetes was induced by a single intraperitoneal injection of streptozotocin (60 mg/kg) in normal rats fasted for 16 h. Subsequently, 30 diabetic male rats were divided into groups and treated orally for 21 days with distilled water (10 mL/kg), glibenclamide (3 mg/kg) and AEEF (300, 400, and 500 mg/kg). Body weight, food and water intake, blood glucose, insulin levels, lipid and oxidative profiles, as well as some markers of liver and kidney function were assessed. Histological sections of the rats' pancreas were taken. Results: AEEF and glibenclamide significantly increased (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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