Evaluation of minimum inhibitory and minimum bactericidal concentration of nano-silver base inorganic anti-microbial agent (Novaron® ) against streptococcus mutans
| Autor: | Goda Holla, Ramakrishna Yeluri, Autar Krishen Munshi |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Contemporary Clinical Dentistry, Vol 3, Iss 3, Pp 288-293 (2012) |
| Druh dokumentu: | article |
| ISSN: | 0976-237X 0976-2361 |
| DOI: | 10.4103/0976-237X.103620 |
| Popis: | Objective: We attempted to find the possibility of determining the minimum inhibitory concentration and minimum bactericidal concentration needed for nano-silver base inorganic anti-microbial agent (Novaron® AG 300, AG 1100) against Streptococcus mutans in vitro using broth dilution assay. Materials and Methods: An ampoule of freeze-dried S. mutans NCTC reference strain was revived, and the colony-forming units (CFU) were calculated. The MIC and MBC was determined by broth dilution assay using different concentrations of Novaron® AG 300 and Novaron® AG 1100 against 1 x 10 5 CFU/ml of S. mutans. Results: The MIC and MBC of Novaron® AG 300 and Novaron® AG 1100 against S. mutans were found to be 40 μg/ml. Conclusions: Novaron® has anti-bacterial effect against S. mutans. Further studies are needed to explore the applicability of these silver-supported anti- microbial agents in clinical dentistry. |
| Databáze: | Directory of Open Access Journals |
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