Severe acute hepatitis by coinfection by epstein-barr viruses and citomegalovirus - case report and review of literature

Autor: Ítalo Renato Valero Román, Grecia Claussen-Portocarrero, Alexander Paucar-Ancassi, Jaime Silva-Diaz
Jazyk: Spanish; Castilian
Rok vydání: 2020
Předmět:
Zdroj: Revista de la Facultad de Medicina Humana, Vol 20, Iss 1, Pp 158-161 (2020)
Druh dokumentu: article
ISSN: 1814-5469
2308-0531
DOI: 10.25176/RFMH.v20i1.2253
Popis: We report the case of a 6-year-old patient with a history of atopic dermatitis. Some days before her hospitalization she presented rhinorrhea and cough. Subsequently she presented maculopapular lesions, increase of body temperature and yellowing of the skin. After being hospitalized, in addition to the symptoms described, she presented 2 episodes of spontaneous epistaxis, hematemesis and melena; while in the physical examination, mucocutaneous jaundice, fever, generalized maculopapular rash, lymphadenopathy, and hepatosplenomegaly were evident. In the images studies, signs that indirectly indicated acute hepatitis and pleural effusion, were found. On the other hand, among the serological results, it was found that the markers of acute infection by EBV and CMV, as well as the marker of chronic EBV infection, were positive. As far as we know, this is the first report of CMV-EBV coinfection in our, due to an acute CMV infection. We report the case and we carry out a review of the literature.
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