Autoimmune thrombotic thrombocytopenic purpura associated with disseminated sarcoidosis: A case report

Autor: Maxime Billotte, Peter Eszto, Benoît Thomas, Pierre Groizard, Pierre Perez, Julien Campagne
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: eJHaem, Vol 5, Iss 1, Pp 225-230 (2024)
Druh dokumentu: article
ISSN: 2688-6146
DOI: 10.1002/jha2.848
Popis: Abstract Sarcoidosis is an inflammatory disease known to be associated with multiple autoimmune disorders. There is a restricted number of descriptions of the association between sarcoidosis and autoimmune thrombotic thrombocytopenic purpura (aTTP). We present the case of a 63‐year‐old woman admitted to the hospital to investigate a possible sarcoidosis who had hemolytic anemia and thrombocytopenia, with low ADAMTS13 activity and anti‐ADAMTS13 antibodies, leading to a diagnosis of aTTP. Sarcoidosis was later confirmed and the two conditions evolved separately after 6 months, questioning the link between them. Clinicians should be aware of this rare cause of thrombocytopenia in patients with sarcoidosis, as aTTP is a life‐threatening condition.
Databáze: Directory of Open Access Journals