Haploidentical hematopoietic cell transplant recipient presents with late‐onset Epstein Barr virus‐associated posttransplant lymphoproliferative disorder

Autor: Adam Braun, Lawrence Liu, Monzr M. Al Malki, Pamela S Becker
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: eJHaem, Vol 4, Iss 3, Pp 848-851 (2023)
Druh dokumentu: article
ISSN: 2688-6146
DOI: 10.1002/jha2.707
Popis: Abstract Posttransplant lymphoproliferative disease (PTLD) is a potentially life‐threatening complication of hematopoietic cell transplantation. With improvements in Epstein‐Barr virus (EBV) monitoring and supportive care, PTLD incidence has decreased throughout the history of bone marrow transplantation. It is rare to develop PTLD after the first year following transplant, across all donor categories. In this case, we hope to elucidate details that may have predisposed to this unusual presentation. We present the case of a 55‐year‐old gentleman with acute myeloid leukemia who underwent a haploidentical transplant for consolidation and presented with fatigue, lethargy and presumed septic shock nearly 7 years after transplant.
Databáze: Directory of Open Access Journals