Delta neutrophil index (DNI) as a potential biomarker for fetal growth restriction: insights from maternal hematological changes and neonatal outcomes

Autor:	Nazan Vanli Tonyali, Kemal Sarsmaz, Burak Bayraktar, Neval Cayonu Kahraman, Serap Topkara Sucu, Gizem Aktemur, Betul Tokgoz Cakir, Zeynep Seyhanli, Gulsan Karabay, Ayberk Cakir, Yaprak Ustun
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Fetal growth restriction Delta neutrophil index Neutrophil to lymphocyte ratio Platelet to lymphocyte ratio Monocyte to lymphocyte ratio Perinatal outcomes Gynecology and obstetrics RG1-991
Zdroj:	BMC Pregnancy and Childbirth, Vol 24, Iss 1, Pp 1-8 (2024)
Druh dokumentu:	article
ISSN:	1471-2393
DOI:	10.1186/s12884-024-06853-w
Popis:	Abstract Background This study investigates the role of Delta Neutrophil Index (DNI), an inflammation marker, in late-onset fetal growth restriction (LO-FGR) and its prediction of composite adverse neonatal outcomes. Methods A retrospective study was conducted on 684 pregnant women (456 with normal fetal development and 228 with LO-FGR) who delivered at Health Sciences University Etlik Zubeyde Hanim Women’s Health Training and Research Hospital between January 1, 2015, and June 30, 2018. Composite adverse neonatal outcomes were defined as at least one of the following: 5th minute APGAR score -2.9, yielding a sensitivity of 78.41%, a specificity of 52.97%, a positive likelihood ratio (+ LR) of 1.68, and a negative likelihood ratio (-LR) of 0.37 (p -2.2, a sensitivity of 69.90%, a specificity of 55.36%, a + LR of 1.56, and a -LR of 0.51 (p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/cd600c8258b84345aa62090723456253 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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