A Practical Approach to Screening for Strongyloides stercoralis

Autor: Luisa Carnino, Jean-Marc Schwob, Laurent Gétaz, Beatrice Nickel, Andreas Neumayr, Gilles Eperon
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Tropical Medicine and Infectious Disease, Vol 6, Iss 4, p 203 (2021)
Druh dokumentu: article
ISSN: 2414-6366
DOI: 10.3390/tropicalmed6040203
Popis: Strongyloides stercoralis, causative agent of a neglected tropical disease, is a soil-transmitted helminth which may cause lifelong persisting infection due to continuous autoinfection. In the case of immunosuppression, life-threatening hyperinfection and disseminated strongyloidiasis can develop. We propose a pragmatic screening algorithm for latent strongyloidiasis based on epidemiologic exposure and immunosuppression status that can be applied for any kind of immunosuppressive therapy. The algorithm allows the diagnosis of latent strongyloidiasis with optimal accuracy in a well-equipped setting, while for endemic settings where the complete testing array is unavailable, an empiric treatment is generally recommended. Accurate diagnosis and extensive empiric treatment will both contribute to decreasing the current neglect of strongyloidiasis.
Databáze: Directory of Open Access Journals