Immunotherapy 'Shock' a case series of PD-L1 100% and pembrolizumab first-line treatment

Autor: Paul Zarogoulidis, Evaggelia Athanasiou, Theodora Tsiouda, Dimitrios Hatzibougias, Haidong Huang, Chong Bai, Georgia Trakada, Lemonia Veletza, Anastasios Kallianos, Christoforos Kosmidis, Nikolaos Barbetakis, Dimitrios Paliouras, Aggeliki Rapti, Dimitrios Drougas, Wolfgang Hohenforst-Schmidt
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Respiratory Medicine Case Reports, Vol 22, Iss C, Pp 197-202 (2017)
Druh dokumentu: article
ISSN: 2213-0071
DOI: 10.1016/j.rmcr.2017.08.017
Popis: In this decade a “bloom” of novel therapies has been observed for non-small cell lung cancer. We have new tools for the diagnosis of lung cancer and also we can re-biospy easier than before in different lesions and obtain tissue samples in order to investigate whether a patient can receive new targeted therapies. Immunotherapy has been well established previously for other forms of cancer, and nowadays it is also available for lung cancer. There are two immunotherapies for now nivolumab and pembrolizumab which can be administered as second line treatment, the second can also be administered as first-line if there is a programmed death-ligand 1 ≥50% expression.
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