| Autor: |
Hugo G Castelán-Sánchez, Luis Delaye, Rhys PD Inward, Simon Dellicour, Bernardo Gutierrez, Natalia Martinez de la Vina, Celia Boukadida, Oliver G Pybus, Guillermo de Anda Jáuregui, Plinio Guzmán, Marisol Flores-Garrido, Óscar Fontanelli, Maribel Hernández Rosales, Amilcar Meneses, Gabriela Olmedo-Alvarez, Alfredo Heriberto Herrera-Estrella, Alejandro Sánchez-Flores, José Esteban Muñoz-Medina, Andreu Comas-García, Bruno Gómez-Gil, Selene Zárate, Blanca Taboada, Susana López, Carlos F Arias, Moritz UG Kraemer, Antonio Lazcano, Marina Escalera Zamudio |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
eLife, Vol 12 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2050-084X |
| DOI: |
10.7554/eLife.82069 |
| Popis: |
Over 200 different SARS-CoV-2 lineages have been observed in Mexico by November 2021. To investigate lineage replacement dynamics, we applied a phylodynamic approach and explored the evolutionary trajectories of five dominant lineages that circulated during the first year of local transmission. For most lineages, peaks in sampling frequencies coincided with different epidemiological waves of infection in Mexico. Lineages B.1.1.222 and B.1.1.519 exhibited similar dynamics, constituting clades that likely originated in Mexico and persisted for >12 months. Lineages B.1.1.7, P.1 and B.1.617.2 also displayed similar dynamics, characterized by multiple introduction events leading to a few successful extended local transmission chains that persisted for several months. For the largest B.1.617.2 clades, we further explored viral lineage movements across Mexico. Many clades were located within the south region of the country, suggesting that this area played a key role in the spread of SARS-CoV-2 in Mexico. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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