Clinical value of video oculomotor evaluation in the differential diagnosis of multiple system atrophy and Parkinson's disease

Autor:	Dongxiao Zhou, Qian Ma, Haiwei Huang, Xue Xu
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	multiple system atrophy Parkinson's disease video oculomotor evaluation Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Zdroj:	Brain and Behavior, Vol 14, Iss 5, Pp n/a-n/a (2024)
Druh dokumentu:	article
ISSN:	2162-3279
DOI:	10.1002/brb3.3510
Popis:	Abstract Background Multiple system atrophy (MSA) is a neurodegenerative disease that progresses rapidly and has a poor prognosis. This study aimed to assess the value of video oculomotor evaluation (VOE) in the differential diagnosis of MSA and Parkinson's disease (PD). Methods In total, 28 patients with MSA, 31 patients with PD, and 30 age‐ and sex‐matched healthy controls (HC) were screened and included in this study. The evaluation consisted of a gaze‐holding test, smooth pursuit eye movement (SPEM), random saccade, and optokinetic nystagmus (OKN). Results The MSA and PD groups had more abnormalities and decreased SPEM gain than the HC group (64.29%, 35.48%, 10%, p
Databáze:	Directory of Open Access Journals
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