MODERN ISSUES OF ORGANIZING RADIO PHARM PREPARATIONS PRODUCTION BASED ON ⁶⁸GA
| Autor: | O. A. Melnikova, D. N. Muratov, A. F. Sitnikov, E. V. Shorikov, D. Yu. Kobesova |
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| Jazyk: | ruština |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Разработка и регистрация лекарственных средств, Vol 0, Iss 1, Pp 134-136 (2019) |
| Druh dokumentu: | article |
| ISSN: | 2305-2066 2658-5049 |
| Popis: | Functional diagnostics method (scintigraphy), connected with injection of radioactive isotopes with further getting of 2-D image by emitting radiation detection, is widely used in medicine. Scintigraphic visualization of infections and inflammation with ⁶⁸Ga-citrate is powerful diagnostic instrument for patients with inflammation or infection disease. ⁶⁸Ga is short-lived positron emitting radionuclide (half-life time is 67,6 min, positron energy is 2,92 MeV). Such characteristics allowed to get better images of other radiopharmaceuticals with ⁶⁸Ga. Benefits of the drugs, mechanism of mother radionuclide fission is described in the article, as well as equipment for ⁶⁸Ga-citrate synthesis with all the technological processes. Obtained ⁶⁸Ga-citrate is suitable for positron emission tomography diagnostics for infection disease and inflammation detection in clinical practice. |
| Databáze: | Directory of Open Access Journals |
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