Clinical applications and therapeutic potentials of advanced nanoparticles: a comprehensive review on completed human clinical trials

Autor: Ranil Vikraman Kumarasamy, Prabhu Manickam Natarajan, Vidhya Rekha Umapathy, Jeane Rebecca Roy, Monica Mironescu, Chella Perumal Palanisamy
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Nanotechnology, Vol 6 (2024)
Druh dokumentu: article
ISSN: 2673-3013
DOI: 10.3389/fnano.2024.1479993
Popis: Nanoparticles are attractive therapeutic tools due to their distinctive characteristics, including more accurate drug delivery, improved bioavailability, and enhanced targeted therapy. This review offers a comprehensive analysis of the therapeutic potentials of cutting-edge nanoparticles as demonstrated in human clinical trials, based on empirical evidence. Through systematic searches of major scientific databases, relevant studies published up to March 2024 were included, focusing on clinical trials utilizing advanced nanoparticles for therapeutic purposes. The review discusses the diverse applications of nanoparticles in oncology, infectious diseases, neurology, and other medical fields. Additionally, it scrutinizes the safety profiles, efficacy outcomes, and challenges associated with nanoparticle-based therapies. The findings underscore significant progress in translating nanoparticle research into clinical practice and highlight the potential of these innovative platforms to revolutionize medical treatments. This review contributes valuable insights into the growing field of nanoparticle-based therapeutics, fostering a deeper understanding of their clinical applications and implications in medical practice.
Databáze: Directory of Open Access Journals