| Autor: |
Carlos José Dornas Gonçalves Barbosa, Renata de Souza Barreiros, André Franci, Flávia Bittar Brito Arantes, Remo Holanda de Mendonça Furtado, Célia Maria Cassaro Strunz, Tânia Rúbia Flores da Rocha, Luciano Moreira Baracioli, José Antônio Franchini Ramires, Roberto Kalil Filho, José Carlos Nicolau |
| Jazyk: |
angličtina |
| Předmět: |
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| Zdroj: |
Clinics, Vol 74 |
| Druh dokumentu: |
article |
| ISSN: |
1980-5322 |
| DOI: |
10.6061/clinics/2019/e1222 |
| Popis: |
OBJECTIVES: Ischemic stroke (IS) or transient ischemic attack (TIA) history is present in 4-17% of patients with coronary artery disease (CAD). This subgroup of patients is at high risk for both ischemic and bleeding events. The aim of this study was to determine the role of platelet aggregability, coagulation and endogenous fibrinolysis in patients with CAD and previous IS or TIA. METHODS: A prospective case-control study that included 140 stable CAD patients divided into two groups: the CASE group (those with a previous IS/TIA, n=70) and the CONTROL group (those without a previous IS/TIA, n=70). Platelet aggregability (VerifyNow Aspirin® and VerifyNow P2Y12®), coagulation (fibrinogen and thromboelastography by Reorox®) and endogenous fibrinolysis (D dimer and plasminogen activator inhibitor-1) were evaluated. RESULTS: Patients in the CASE group presented significantly higher systolic blood pressure levels (135.84±16.09 vs 123.68±16.11, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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