Research progress in the diagnosis and treatment of neurotrophic keratitis

Autor: Yang Cici, Geng Yuqian, Liu Yi
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Guoji Yanke Zazhi, Vol 24, Iss 1, Pp 67-71 (2024)
Druh dokumentu: article
ISSN: 1672-5123
DOI: 10.3980/j.issn.1672-5123.2024.1.13
Popis: Neurotrophic keratitis(NK)is a degenerative corneal disease caused by impairment of trigeminal innervations. It can lead to spontaneous corneal epithelial defects, corneal ulceration and perforation. Early diagnosis of NK is crucial and requires accurate investigation of clinical history and thorough examination of ocular surface to determine clinical stage. Treatment for NK needs to be divided into stages according to disease severity. In addition to conventional treatments including artificial tears, blepharorrhaphy, and amniotic membrane transplantation, there are also emerging treatments such as targeted drug therapy and corneal neurotization. This article summarized the epidemiology, clinical manifestations and classification, etiology, diagnosis, differential diagnosis and treatment of NK, aiming to provide reference for the early diagnosis and treatment of NK in the future.
Databáze: Directory of Open Access Journals