Vibration influence on functional activity of nervous system in experimental animals
| Autor: | V. A. Pankov, M. V. Kuleshova, E. V. Katamanova, N. V. Kartapoltseva |
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| Jazyk: | ruština |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Acta Biomedica Scientifica, Vol 0, Iss 3(2), Pp 113-119 (2013) |
| Druh dokumentu: | article |
| ISSN: | 2541-9420 2587-9596 90518144 |
| Popis: | The production vibration is known to be a powerful stressor which may induce the complex of disorders leading to the vibration-induced disease development. Along with the appearance of the clinical syndromes the neurosis-like, the psychoemotional disorders, the ipochondric, asthenic and asthenovegetative syndromes, the diffuse disorders of the bioelectrical brain activity with the participation of the cortex of the large hemispheres as well as the stem and diencephalic brain structures were observed to occur in the patients with the vibration-induced disease. However, at present there are no clear arguments in favour that namely the exposure to vibration may promote the occurrence of the neurotic disorders, the neurosis-like disorders of psychic activity, the disadaptation signs, the emotional disorders as well as the pathological changes in the bioelectrical brain activity in exposure to vibration. This work aimed to reveal the changes in the central nervous system (CNS) based on the study results of the behavior and bioelectrical brain activity in the animals. The experimental studies were performed using the mature inbreeding rats males. The chronic experiment was performed by means of the modificated vibrostend VEDS-10a, the vibration levels taken corresponded to the exposure in reality to vibration under production conditions. The studies were performed based on 4 study series: for 15 days, one, two, and four months of exposure to vibration. The intact rats were used as the control ones. The animal behavior responses with assessing the motor activity, the orientating and learning as well as the emotional behavior components were observed in the «юрen field». Recording and processing the electroencephalographic data were performed using the electroencephalograph Neuron-spectrum 4 (Joint-Stock Company «Neurosoft», Russia). The information was processed using the standard methods of the variation statistica, statistical processing the data was performed by means of the Packet of Applied Programs EXCEL Packet Office 2003 (in OS «W1NDOWS Xp»), «Statistica for windows - Version 6». The study of the behavior activity in the animals has shown that the increase in the common motor activity, the nonspecific character, the high emotional strain of the negative character, the negative emotional state were found to occur in the rats exposed to vibration, thereto, the orientating and learning activity was at the previous level. The change in the bioelectrical brain activity was characterized by the increase in the slow-wave activity of the delta-range after one month of exposure to vibration and the latent period prolongation of the visual induced potentials (V1P) after 15 days of exposure to vibration. |
| Databáze: | Directory of Open Access Journals |
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