Clinical and laboratory substantiation of monarda hydrolate application in complex therapy of mycoses
| Autor: | Prokhorov Dmitry, Eliseeva Valeriya, Postnikova Olga, Sataieva Tatiana, Shevchuk Oksana, Bakova Nadezhda, Suslova Anna |
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| Jazyk: | English<br />French |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | BIO Web of Conferences, Vol 138, p 04002 (2024) |
| Druh dokumentu: | article |
| ISSN: | 2117-4458 20241380 |
| DOI: | 10.1051/bioconf/202413804002 |
| Popis: | This article presents the results of the study of the effect of monarda hydrolate on the growth of opportunistic microorganisms, Staphylococcus aureus, Escherichia coli, Candida albicans, as well as the effectiveness and safety of monarda hydrolate in the complex therapy of mycoses on the example of patients diagnosed with mycosis of the trunk and variegated lichen planus. The obtained experimental data indicate a pronounced antibacterial and antifungal action of biologically active substances of the plant. When hydrolate was added to the nutrient medium, growth suppression was as follows: S.aureus - 92.2%, E.suli - 90.8%, C.albicans - 95.5%. Monarda hydrolat demonstrated high safety and efficacy in the treatment of mycoses of the skin: in all patients studied there was a complete clinical and microbiological recovery, regression of rashes was achieved faster than when using standard antifungal therapy. It should be noted that two patients during the use of hydrolat observed manifestations of contact dermatitis, but it spontaneously resolved within a few days and patients continued therapy. Thus, the external use of monarda hydrolate in combination with other drugs can be considered as an alternative method of treatment of fungal skin diseases, especially in cases of frequent recurrences of the disease and formed resistance. |
| Databáze: | Directory of Open Access Journals |
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