| Autor: |
Nur Kesiktaş, Nurten Eskiyurt, Ayşe Karan, Semih Akı, Halim İşsever |
| Jazyk: |
English<br />Turkish |
| Rok vydání: |
2009 |
| Předmět: |
|
| Zdroj: |
Türk Osteoporoz Dergisi, Vol 15, Iss 1, Pp 1-6 (2009) |
| Druh dokumentu: |
article |
| ISSN: |
2147-2653 |
| Popis: |
Aim: Although vitamin B12 (vit-B12) is known to influence the hemopoeitic and nervous systems, little is known about the skeletal effects of vit-B12. Researchs that demonstrated an association between serum vitamin B-12 concentration and osteoblastic function and its’ role in DNA synthesis, which suggesting a relationship between osteoporosis, this randomized controlled trial were planned. Material and Methods: Vit-B12 levels of 740 patients aged between 50-65 years, who were applied to our outpatient clinic because of chronic low back pain were examined and divided with vitamin B-12 levels over or below 400 pg/ml. 26 participant who met all inclusion criteria with vit-B12 level below 400pg/ml were assigned to case group. Among the patients that vit-B12 levels were over 400pg/ml, 20 participants were randomly selected to control group. Bone mineral density (BMD), biochemical measurements, causes of osteoporosis and vit-B12 defiencies were investigated. A computer program was used for statistic evaluation. Results: There was not statistically significant difference between BMD’s of case and control groups (p>0.05). When the vit-B12 levels were grouped with over 400 pg/ml, below 200 pg/ml and between 200-400 pg/ml, osteodensimetric examinations of femur neck BMD (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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