Development of synthetic antigen vaccines for COVID-19
| Autor: | Maria da Conceição Viana Invenção, Alanne Rayssa da Silva Melo, Larissa Silva de Macêdo, Thaís Souto Paula da Costa Neves, Cristiane Moutinho Lagos de Melo, Marcelo Nazário Cordeiro, Marcus Vinicius de Aragão Batista, Antonio Carlos de Freitas |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Human Vaccines & Immunotherapeutics, Vol 17, Iss 11, Pp 3855-3870 (2021) |
| Druh dokumentu: | article |
| ISSN: | 2164-5515 2164-554X 21645515 |
| DOI: | 10.1080/21645515.2021.1974288 |
| Popis: | The current pandemic called COVID-19 caused by the SARS-CoV-2 virus brought the need for the search for fast alternatives to both control and fight the SARS-CoV-2 infection. Therefore, a race for a vaccine against COVID-19 took place, and some vaccines have been approved for emergency use in several countries in a record time. Ongoing prophylactic research has sought faster, safer, and precise alternatives by redirecting knowledge of other vaccines, and/or the development of new strategies using available tools, mainly in the areas of genomics and bioinformatics. The current review highlights the development of synthetic antigen vaccines, focusing on the usage of bioinformatics tools for the selection and construction of antigens on the different vaccine constructions under development, as well as strategies to optimize vaccines for COVID-19. |
| Databáze: | Directory of Open Access Journals |
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