Commercialized Hybrid Closed-Loop System (Minimed Medtronic 670G) Results During Pregnancy

Autor: Jesús Moreno-Fernández, PhD, MD, José Alberto García-Seco, RN, PhD
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: AACE Clinical Case Reports, Vol 7, Iss 3, Pp 177-179 (2021)
Druh dokumentu: article
ISSN: 2376-0605
DOI: 10.1016/j.aace.2020.11.039
Popis: Objective: Hybrid closed-loop (HCL) devices can achieve tight glycemic control but are rarely used in pregnancy, which remains an off-label indication. We present a case of a pregnant patient with type 1 diabetes mellitus (T1DM) who used the Medtronic MiniMed 670G HCL system. Methods: MiniMed 670G includes an advanced automode option (HCL therapy), which our patient used from the first trimester to the end of the pregnancy. Results: An unplanned pregnancy was detected in the T1DM patient, with a glycated hemoglobin level of 8.7 mmol/L (7.1%). The patient started sensor-augmented pump therapy at week 13. Subsequently, she entered automode (HCL) at week 16. The time in range (3.7-7.8 mmol/mol, 63-140 mg/dL) increased from 46.8% to 51.3% after HCL initiation. The glycated hemoglobin level remained close to 48 mmol/mol (6.5%) until the end of the pregnancy. Furthermore, the time under range (
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