Analysis of possible food/nutrient and drug interactions in hospitalized patients
| Autor: | Everton Moraes Lopes, Rumão Batista Nunes de Carvalho, Rivelilson Mendes de Freitas |
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| Jazyk: | English<br />Portuguese |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | Einstein (São Paulo), Vol 8, Iss 3, Pp 298-302 (2010) |
| Druh dokumentu: | article |
| ISSN: | 2317-6385 1679-4508 |
| DOI: | 10.1590/s1679-45082010ao1672 |
| Popis: | ABSTRACT Objective: To evaluate the prescription in relation to the possible interactions between drugs and foods/nutrients in the diets of patients in the Hospital Regional Justino Luz in the municipality of Picos, Piauí, Brazil. Methods: The sample consisted of 60 medical records of patients admitted at the hospital. The records were analyzed according to the presence or absence of interactions between drugs and foods/nutrients of the prescribed diets. Results: Of the 82 drugs prescribed in all periods, there were 16 drugs (19.5%) with possible interaction with food, a total of 60 interactions between nutrient/food and medicine. Thus, 18 (30%), 10 (17%) and 8 (13%) possible interactions were identified with captopril (cardiovascular drug) with acetylsalicylic acid (anti-inflammatory) and spironolactone (diuretic), respectively representing the highest numbers of interactions among the classes of investigated drugs. It was also found that the total interactions between food/nutrients and drugs, 32 (53%) accounted for interactions with cardiovascular drugs, 13 (22%) with anti-inflammatory drugs, 11 (18%) with diuretic agents e 4 (7%) with drugs that act on the digestive tract. Conclusion: There was a high number of interactions between food/nutrients and medicines emphasizing the need for prior knowledge of these interactions as a way to avoid impairment in the treatment, longer hospital stays and/or damage to the nutritional status of the patients. |
| Databáze: | Directory of Open Access Journals |
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