Positive Retrospective SARS-CoV-2 Testing in a Case of Acute Respiratory Distress Syndrome of Unknown Etiology.

Autor:	A. Burkett, S. McElwee, C. Margaroli, P. Bajpai, A. Elkholy, U. Manne, K. Wille, P. Benson
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Diseases of the respiratory system RC705-779
Zdroj:	Case Reports in Pulmonology, Vol 2021 (2021)
Druh dokumentu:	article
ISSN:	2090-6846 2090-6854
DOI:	10.1155/2021/5484239
Popis:	In order to elucidate the cause of acute respiratory distress syndrome of unknown etiology in a pre-pandemic patient, molecular techniques were used for detection of SARS-CoV-2. We used a SARS-CoV-2 nucleocapsid protein immunofluorescence stain to retrospectively identify an individual with diffuse alveolar damage on autopsy histology who had negative respiratory virus panel results in February, 2020, in Birmingham, Alabama. In situ hybridization for SARS-CoV-2 RNA revealed evidence of widespread multiorgan SARS-CoV-2 infection. This death antecedes the first reported death of a State of Alabama resident diagnosed with SARS-CoV-2 by 26 days.
Databáze:	Directory of Open Access Journals
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