Hematological Manifestations of Dengue, Malaria and Enteric Fever in Children Presenting To a Tertiary Care Hospital, Pakistan

Autor: sharmeen Nasir, Muhammad Rafique, Ammarah Jamal, Waseem Jamalvi, Yousuf Yahya
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Annals of Abbasi Shaheed Hospital and Karachi Medical & Dental College, Vol 29, Iss 2 (2024)
Druh dokumentu: article
ISSN: 1563-3241
DOI: 10.58397/ashkmdc.v29i2.710
Popis: Objective: Dengue fever, Malaria and Enteric fever are common pediatric acute febrile illnesses, pre- senting with overlapping clinical manifestations. The hematological parameters of these disease may give a clue to the specific diagnosis before definitive investigations are available. We designed this study to determine the hematological predictors of dengue fever, malaria and enteric fever in pediatric inpatient population. Methods: We collected data for this observational study from May to October 2022 from Pediatrics De- partment, Dr. RKMP Civil Hospital Karachi. We reviewed the medical records of patients 1 month to 12 years of age admitted with definitive diagnosis of dengue, malaria and/or enteric fever. We re- corded the demographic and clinical variables and hematologic parameters of Complete Blood Count and calculated the P value and sensitivity / specificity of each parameter in SPSS 22.0, for differentiating the three diseases. Results: A total of 205 patients were included in the study, out of which 82 (40%) had malaria, 71 (34.6%) had dengue and 52 (25.4%) had enteric fever. Male gender was predominant in 73.6%. Patients with dengue fever mostly had normal hemoglobin (>11gm/dl) with a higher hematocrit, lymphopenia (
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