4-Phenyl-1-(prop-2-yn-1-yl)-1H-1,5-benzodiazepin-2(3H)-one
| Autor: | Mohamed Loughzail, José A. Fernandes, Abdesselam Baouid, Mohamed Essaber, José A. S. Cavaleiro, Filipe A. Almeida Paz |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Acta Crystallographica Section E, Vol 67, Iss 8, Pp o2075-o2076 (2011) |
| Druh dokumentu: | article |
| ISSN: | 16005368 1600-5368 |
| DOI: | 10.1107/S1600536811027371 |
| Popis: | 4-Phenyl-1H-1,5-benzodiazepin-2(3H)-one reacts in the presence of a concentrated aqueous solution of sodium hydroxide and a quaternary ammonium salt (as catalyst) in benzene (phase transfer catalysis) with propargyl bromide, affording the title benzodiazepine derivative, C18H14N2O. In the molecule, the mean plane of the propargyl substituent is almost perpendicular with that of the amide group [dihedral angle = 87.81 (8)°]. In the crystal, the molecules are linked by C—H...O and C—H...N interactions. |
| Databáze: | Directory of Open Access Journals |
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