Effects of comorbid conditions and prescribed chronic medications on the treatment plan for chronic hepatitis C infection: A cross‐sectional retrospective study

Autor: Abdullah Awadh, Ziyad Badri, Nayef Alansari, Ahmed Alkhiri, Hussein Baharoon, Abdelulah Niaz, Alaa Al‐Kathiri, Enas Ghulam, Mohammad Khan
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Health Science Reports, Vol 7, Iss 5, Pp n/a-n/a (2024)
Druh dokumentu: article
ISSN: 2398-8835
DOI: 10.1002/hsr2.2055
Popis: Abstract Background Chronic hepatitis C (CHC) infection is a potentially life‐threatening condition characterized by various complications, including end‐stage liver disease and cirrhosis. The mortality rate associated with CHC has been increasing due to the presence of comorbidities and the use of chronic medications. Therefore, the objective of this study was to investigate the impact of these comorbidities and chronic medications on the treatment plan for CHC. Methods To achieve this objective, a cross‐sectional retrospective study was conducted at a tertiary hospital in Jeddah, Saudi Arabia. The study population included patients aged 12 years and above who were diagnosed with CHC between 2016 and 2021. Patients below the age of 12 were excluded from the study. A total of 170 patients with CHC were included in the analysis. The study aimed to evaluate the relationship between CHC complications and the treatment approach. Results The mean age of the study participants was 66.78 years, with a higher proportion of female patients. The findings revealed a significant association between hypertension (p = 0.042) and cirrhosis (p = 0.007) with changes in the treatment plan for CHC. Moreover, the presence of diabetes mellitus (p = 0.045), renal diseases (p
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