Biocompatibility of photopolymers for additive manufacturing

Autor: Leonhardt Stefan, Klare Martin, Scheer Maurice, Fischer Theresa, Cordes Burghard, Eblenkamp Markus
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Current Directions in Biomedical Engineering, Vol 2, Iss 1, Pp 113-116 (2016)
Druh dokumentu: article
ISSN: 2364-5504
DOI: 10.1515/cdbme-2016-0028
Popis: To establish photopolymers for the production of class II or class III medical products by additive manufacturing it is essential to know which components of photopolymeric systems, consisting of monomers, photoinitiators and additives, are the determining factors on their biocompatible properties. In this study the leachable substances of a cured photopolymeric system were eluted and identified by HPLC-MS detection. In addition the cured photopolymer was testes for cytotoxicity and genotoxicity according to DIN EN ISO 10993 for long time applications. The results showed that uncured residual monomers are the determining factor on the biocompatible properties of the photopolymeric system. Strategies to reduce these residual monomers in the cured photopolymer are presented.
Databáze: Directory of Open Access Journals