Olfactory marker protein directly buffers cAMP to avoid depolarization-induced silencing of olfactory receptor neurons
| Autor: | Noriyuki Nakashima, Kie Nakashima, Akiko Taura, Akiko Takaku-Nakashima, Harunori Ohmori, Makoto Takano |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020) |
| Druh dokumentu: | article |
| ISSN: | 2041-1723 71409998 |
| DOI: | 10.1038/s41467-020-15917-2 |
| Popis: | The physiological role of the olfactory marker protein (OMP) has been elusive. Here, the authors demonstrate that OMP buffers cAMP and modulates cAMP-gated channel activity upon sensory stimulation, maintaining neuronal firing during odour-source searching. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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